While the story content of
Amazing Spider-Man Annual #2 consists mostly of reprints of prior ASM tales by Stan Lee and Steve Ditko (along with additional rogues gallery profiles), the issue's lead story is impressive original material by the same writer/artist team and offers the first meeting between Spider-Man and Dr. Strange, Master of the Mystic Arts, as well as the first appearance by the sorcerer who calls himself
Xandu the Unspeakable, or Xandu the All Powerful, or whatever adjective suits his whimsy when announcing himself to others. But to clear up one thing right away, Xandu is not to be confused with Shangdu, one of three capital cities of Kublai Khan's Yuan Dynasty--a city otherwise known by a name which became attached to one of the biggest box office disappointments of 1980.
Too bad, Xandu--one more letter and your name would have been up in lights. Briefly.
As it happened, this 1965 story also came in handy about 3½ years later during the short run of the first Doctor Strange series, presumably as a way to entice readers to try the book. It was something of a red flag to see a reprint appearing so soon in a still-nascent series--in this case, just four issues prior to the title's cancellation.
(Trivia note: Ditko's standing image of Spider-Man just took a bit of mirroring to become a classic corner box.)
As for what Xandu has in mind, he'll first need a little hired muscle to pull it off--that is to say, enslaved muscle, in the form of two bar room bruisers who were accustomed to throwing their weight around.
And just in case you were wondering who had custody of the other half of the mystic wand Xandu covets, it indeed happens to be Dr. Strange--though not for long, as his attackers are not susceptible to a mystic defense given their current state.
All of which paves the way to a fine original story with what seems to be a very off-brand title for a Spider-Man issue. (More than likely another pitch to Spidey readers to check out a character still playing second fiddle to Nick Fury at this point in time. Sheesh! Can the hard sell already, Stan!)